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Seeking medical advice See a GP if you're concerned that you may have symptoms of Parkinson's disease. Find out more about diagnosing Parkinson's disease Causes of Parkinson's disease Parkinson's disease is caused by a loss of nerve cells in part of the brain called the substantia nigra. Dopamine plays a vital role in regulating the movement of the body. A reduction in dopamine is responsible for many of the symptoms of Parkinson's disease. Exactly what causes the loss of nerve cells is unclear. Seeking a real woman 50 experts think that a combination of genetic and environmental factors is responsible.
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